Advancing Prostate Cancer Outcomes Through Big Data Research
From PIONEER to PIONEER+
Public-Private Partnership
A public-private partnership under the Innovative Medicines Initiative (IMI) bringing together academia and industry.
Big Data Focus
Aimed to improve outcomes and care for prostate cancer patients through the use of big data and real-world evidence.
Comprehensive Platform
Developed a comprehensive data platform integrating clinical, genomic, and patient-reported data across Europe.
Be Part of PIONEER+ Research That Matters
Learn More About PIONEER+ Legacy
Discover the full scope of PIONEER+ contributions to prostate cancer research and clinical practice.
Access Prostate Cancer Outcome Tools
Utilize PIONEER+ validated tools and frameworks for measuring prostate cancer outcomes in your practice.
Join a Multi-Stakeholder Membership Group
Be part of a collaborative network tackling the most important questions in prostate cancer. Contribute your expertise, help define research questions, and turn data into insights that improve care across Europe.
PIONEER+ Lasting Impact
Federated Data Infrastructure
Established a federated data infrastructure to securely analyse prostate cancer datasets across multiple institutions and countries.
Core Outcome Sets
Defined core outcome sets for prostate cancer, emphasizing outcomes that matter most to patients.
EAU Guidelines Integration
Developed tools and evidence that directly feed into EAU Guidelines and decision-making pathways.
Harmonisation and Interoperability
Making effective use of harmonised datasets for real-world research applications, laying the foundation for breakthroughs in urological care.
Sustainability through the UroEvidenceHub
Following the end of the IMI funding period, PIONEER+ sustainability arm ensures the continued use and expansion of:
Data Models & Ontologies
Data models and ontologies for prostate cancer research and clinical practice.
Federated Analytics Tools
Federated analytics tools built for multi-institutional collaboration and secure data sharing.
Outcome Standardization
Outcome standardization frameworks, including PROMs for consistent measurement across studies.
Training & Governance
Training, governance, and open science initiatives to support the research community.
Why it Matters
Continued Access
Researchers and clinicians across Europe can continue using PIONEER+ tools and models to drive meaningful insights.
Guideline Relevance
PIONEER+ data continues to inform the development and refinement of EAU clinical guidelines.
Sustainable Innovation
The PIONEER+ infrastructure is not a finished project—it's a living foundation for future discovery and improvement in prostate cancer care.
Continue the PIONEER+ Legacy
All PIONEER+ innovations are now being maintained and evolved within the UEH ecosystem, supporting ongoing innovation and clinical application.
Contact: datainnovation@uroweb.org
PIONEER+ was supported by the Innovative Medicines Initiative (IMI) under grant agreement No 777492.
Sustainability and ongoing development are now managed through the EAU UroEvidenceHub.